Increased Antimycobacterial Immunity in Interleukin-10-Deficient Mice
نویسندگان
چکیده
منابع مشابه
Increased antimycobacterial immunity in interleukin-10-deficient mice.
Macrophage effector functions are essential for clearing mycobacterial infections. Interleukin 10 (IL-10) negatively regulates macrophages and could be a factor inhibiting effective antimycobacterial immunity. We previously showed that transgenic mice which produce excess IL-10 from T cells are susceptible to infection, even though these mice continue to produce gamma interferon (IFN-gamma) at ...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1999
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.67.6.3087-3095.1999